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Melatonin after Four Decades


Annotation
Reviews 40 years of research; human & animal, basic science & clinical; measuring techniques; more

From The Critics
Booknews
Fifty-six contributions document a wide range of research contributions from most of the major laboratories in the field of melatonin research, as presented in a special conference to mark the 40 year anniversary of the isolation and chemical identification of this hormone. A number of chapters written by younger scientists provide a glimpse of future work in melatonin research. Topics addressed vary widely and include the effects of vasoactive intestinal peptide and histamine on melatonin and cAMP production in chick embryo pineal cells; the role of cGMP and nitric oxide in the photoendocrine signal transduction in pineal photoreceptors of the trout; molecular pharmacology and function of melatonin receptor subtypes; the roles of melatonin in development; melatonin and cardiovascular function; cytochalasin B influence on megakaryocyte patch-clamp; MLT and the immune-hematopoietic system; and a preliminary report on circadian serum melatonin profiles in patients with very large goitre before and after surgery. Annotation c. Book News, Inc., Portland, OR (booknews.com)


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